Occupational ultraviolet exposure and risk of non-Hodgkin’s lymphomas: a meta-analysis
نویسندگان
چکیده
Non-Hodgkin lymphoma is a heterogeneous group of lympho-proliferative disorders. We performed a meta-analysis to summarize the available evidence from case-control studies and cohort study on the inconsistent association between occupational sun exposure and the risk of non-Hodgkin lymphoma. We searched PubMed, ISI web of science, the Cochrane Library, EMBASE and reference lists for relevant articles. Study specific odds ratios or relative risk and 95% confidence intervals were pooled by using fixed-effects or random-effects models. Ten case-control studies and one cohort study were included in the meta-analysis. Overall, the pooled odds ratios for occupational ultraviolet exposure and non-Hodgkin lymphoma risk was 1.15(95% confidence intervals: 0.99, 1.32; I2 = 44.4%). Occupational sun exposure was positively associated with the risk of NHL 1.14 (95% confidence intervals: 1.05, 1.23; I2=25.4% p for heterogeneity =0.202) in Caucasian population. Common subtypes of non-Hodgkin lymphoma and ultraviolet exposure had the negative results. The pooled odds ratios was 1.16, (95%confidence intervals: 0.90, 1.50) for T-cell non-Hodgkin lymphoma; 0.79, (95%confidence intervals: 0.61, 1.02) for B-cell non-Hodgkin lymphoma; 1.13, (95%confidence intervals: 0.96, 1.34) for chronic lymphocytic leukemia; 1.25, (95%confidence intervals: 0.95, 1.64) for males; 1.49, (95%confidence intervals: 0.99, 2.25) for females. Data suggested that occupational ultraviolet exposure was a risk factor for non-Hodgkin lymphoma in Caucasian population. While, there had no relationship between occupational ultraviolet exposure and risk of non-Hodgkin lymphoma in general population as well as non-Hodgkin lymphoma common subtypes. Besides, gender specific occupational sun exposure also indicated no association on risk of non-Hodgkin lymphoma.
منابع مشابه
Non-Hodgkin Lymphoma (NHL) in Pakistan
Lymphomas are classified as Hodgkin’s and Non-Hodgkin’s lymphomas (HL NHL) NHL being further sub-divided into B, T and Null cell categories on the basis of WHO classification. With a few exceptions worldwide, B-NHL are more common, accounting approximately 80-85% of all cases of NHL compared to T-NHL, which accounts for about 10-15% of all NHL cases. The incidence of NHL has shown a steady incr...
متن کاملTc-99m MIBI imaging in lymphomas: Comparison with T1-201 and Ga-67 scientigraphy
Tc-99m MIBI has recently been used in the functional imaging of various tumors. This prospective study was performed to evaluate the role of Tc-99m MIBI imaging at the time of the initial staging, assessment of treatment response, follow-up studies and survaillance in Hodgkin’s and non-Hodgkin’s Iymphoma. 25 patients (14 with Hodgkin’s and 11 with non-Hodgkin’s Iymphoma) underwent 32 stud...
متن کاملExtranodal Non-Hodgkin’s Lymphoma of the Oral Cavity: A Case Report
Lymphomas are solid malignant tumors having a wide spectrum of clinical and pathological features. Non-Hodgkin’s lymphoma (NHL) is a subtype of lymphoma with two-thirds of the cases presenting as lymph node enlargement. The remaining one third of NHL cases has been reported in the extranodal sites, including the gastro intestinal tract, Waldeyer’s ring, bone, skin, and brain. Intraoral non-Hodg...
متن کاملبررسی میزان مواجهه شغلی با پرتوهای غیریونساز و اثربخشی وسایل حفاظت فردی در انواع جوشکاری قوس الکتریکی متداول
Introduction: Welding is considered to be one of the main sources of occupational exposure to non ionizing radiations. The present study was conducted to examine the rate of occupational exposure to non-ionizing radiation in common welding processes. Materials and Methods: In the present descriptive analytical study, occupational exposure to different types of non-ionizing radiations in...
متن کامل